1. Pharmaceutical Intermediates
Bortezomib Acid Impurity: That is an impurity connected to bortezomib, a proteasome inhibitor Employed in the remedy of a number of myeloma. Its synthesis or examine is essential for guaranteeing the purity and safety of the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor from the synthesis of abiraterone acetate, a drug Utilized in the therapy of prostate most cancers by inhibiting androgen creation.
Imatinib Intermediate (CAS NO. 152460-10-1): A important compound within the synthesis of imatinib, a drug that targets specific varieties of most cancers, which include Continual myelogenous leukemia (CML).
Docetaxel Intermediate: A compound Employed in the synthesis of docetaxel, a chemotherapy medication that treats a variety of cancers like breast, lung, and prostate most cancers.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, 8): They're intermediates during the synthesis of gemcitabine, an anti-most cancers drug. Their study is vital for optimizing the manufacturing procedure and ensuring significant purity.
Lapatinib Intermediate (CAS NO. 231278-eighty four-five): Lapatinib is employed to treat breast most cancers, and these intermediates are involved with its generation.
Fulvestrant Intermediates: Fulvestrant is definitely an estrogen receptor antagonist Employed in the cure of breast cancer. Several intermediates help in the synthesis of this drug.
Paclitaxel Facet Chain Acid (CAS NO. 949023-sixteen-9): This intermediate is Utilized in the synthesis of paclitaxel, a chemotherapy drug helpful in dealing with cancers for instance ovarian, breast, and lung cancer.
3. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug Employed in the procedure of colorectal most cancers and tiny cell lung most cancers.
3-Amino-one-hydroxyadamantane (CAS 702-eighty two-9): This compound CAS NO.154229-19-3 is linked to the synthesis of adamantane derivatives, that have several applications, like antiviral properties.
Vildagliptin Intermediates: Utilized in the creation of vildagliptin, an oral drug for kind two diabetic issues that inhibits the enzyme DPP-four to manage blood sugar degrees.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-forty eight-1): This compound is associated with the synthesis of varied gluconic 3 acid derivatives, which can be Utilized in foodstuff, pharmaceutical, and industrial programs.
Canagliflozin Intermediate 2: A precursor inside the synthesis of canagliflozin, a medication utilised to control variety 2 diabetes by inhibiting sodium-glucose co-transporter two (SGLT2).